This show has been on my to-watch list for quite a while. I recently saw this webcomic by the talented KC Green, and it finally got me to start trying the show out. So far I've gotten through the first season and a couple of episodes from the second.
It's a pretty formulaic show; this guy House is a genius with attitude problems who loves fixing patients with weird diseases. At the start of every episode, the patient is introduced getting some nasty symptoms, and then House and his crew get ahold of him or her. They then spend about three quarters of the show screwing everything up with incorrect diagnoses, and then House has a lightbulb explode in his head while examining some inconsequential patient and fixes everything. As of yet no patient has died, but I'm told that will happen at some point.
House himself is of course the most interesting part of the show. His acting is very good, and his psychological/physical problems make for some entertaining empathy. The rest of the cast is usually pretty bland with a few shining moments here and there. For some reason though, this show is addicting as freeze-pops, and it supposedly gets even better. It's gonna be a fun ride.
It's not lupus.